This article is about medical terminology.
For other uses, see Malignancy (disambiguation).
"Malignant" redirects here.
For other uses, see Malignant (disambiguation).
Malignancy (from Latin male 'badly', and -gnus 'born') is the tendency of a medical condition to become progressively worse.
Malignancy is most familiar as a characterization of cancer.
A malignant tumor contrasts with a non-cancerous benign tumor in that a malignancy is not self-limited in its growth, is capable of invading into adjacent tissues, and may be capable of spreading to distant tissues.
A benign tumor has none of those properties.
Cancers usually show tumour heterogeneity, containing multiple subclones.
Uses of "malignant" in oncology:
- Malignancy, malignant neoplasm and malignant tumor are synonymous with cancer
- Malignant transformation
Non-oncologic disorders referred to as "malignant":
- Malignant hypertension
- Malignant hyperthermia
- Malignant otitis externa
- Malignant tertian malaria (malaria caused specifically by Plasmodium falciparum)
- Neuroleptic malignant syndrome
Credits to the contents of this page go to the authors of the corresponding Wikipedia page: en.wikipedia.org/wiki/Malignancy.