Type I collagen_table_infobox_0
| collagen, type I, alpha 1Type I collagen_header_cell_0_0_0
|
| IdentifiersType I collagen_header_cell_0_1_0
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| SymbolType I collagen_header_cell_0_2_0
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COL1A1Type I collagen_cell_0_2_1
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| NCBI geneType I collagen_header_cell_0_3_0
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Type I collagen_cell_0_3_1
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| HGNCType I collagen_header_cell_0_4_0
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Type I collagen_cell_0_4_1
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| OMIMType I collagen_header_cell_0_5_0
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Type I collagen_cell_0_5_1
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| RefSeqType I collagen_header_cell_0_6_0
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Type I collagen_cell_0_6_1
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| UniProtType I collagen_header_cell_0_7_0
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Type I collagen_cell_0_7_1
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| Other dataType I collagen_header_cell_0_8_0
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| LocusType I collagen_header_cell_0_9_0
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Chr. 17Type I collagen_cell_0_9_1
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| Search forStructuresDomainsType I collagen_cell_0_10_0
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| Search forType I collagen_header_cell_0_11_0
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| StructuresType I collagen_header_cell_0_12_0
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Type I collagen_cell_0_12_1
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| DomainsType I collagen_header_cell_0_13_0
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Type I collagen_cell_0_13_1
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Type I collagen_table_infobox_1
| collagen, type I, alpha 2Type I collagen_header_cell_1_0_0
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| IdentifiersType I collagen_header_cell_1_1_0
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| SymbolType I collagen_header_cell_1_2_0
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COL1A2Type I collagen_cell_1_2_1
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| Alt. symbolsType I collagen_header_cell_1_3_0
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OI4Type I collagen_cell_1_3_1
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| NCBI geneType I collagen_header_cell_1_4_0
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Type I collagen_cell_1_4_1
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| HGNCType I collagen_header_cell_1_5_0
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Type I collagen_cell_1_5_1
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| OMIMType I collagen_header_cell_1_6_0
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Type I collagen_cell_1_6_1
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| RefSeqType I collagen_header_cell_1_7_0
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Type I collagen_cell_1_7_1
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| UniProtType I collagen_header_cell_1_8_0
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Type I collagen_cell_1_8_1
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| Other dataType I collagen_header_cell_1_9_0
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| LocusType I collagen_header_cell_1_10_0
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Chr. 7Type I collagen_cell_1_10_1
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| Search forStructuresDomainsType I collagen_cell_1_11_0
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| Search forType I collagen_header_cell_1_12_0
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| StructuresType I collagen_header_cell_1_13_0
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Type I collagen_cell_1_13_1
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| DomainsType I collagen_header_cell_1_14_0
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Type I collagen_cell_1_14_1
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Type I collagen is the most abundant collagen of the human body. Type I collagen_sentence_0
It forms large, eosinophilic fibers known as collagen fibers. Type I collagen_sentence_1
It is present in scar tissue, the end product when tissue heals by repair, as well as tendons, ligaments, the endomysium of myofibrils, the organic part of bone, the dermis, the dentin, and organ capsules. Type I collagen_sentence_2
Formation Type I collagen_section_0
The COL1A1 gene produces the pro-alpha1(I) chain. Type I collagen_sentence_3
This chain combines with another pro-alpha1(I) chain and also with a pro-alpha2(I) chain (produced by the COL1A2 gene) to make a molecule of type I procollagen. Type I collagen_sentence_4
These triple-stranded, rope-like procollagen molecules must be processed by enzymes outside the cell. Type I collagen_sentence_5
Once these molecules are processed, they arrange themselves into long, thin fibrils that cross-link to one another in the spaces around cells. Type I collagen_sentence_6
The cross-links result in the formation of very strong mature type I collagen fibers. Type I collagen_sentence_7
Clinical significance Type I collagen_section_1
See Collagen, type I, alpha 1#Clinical significance Type I collagen_sentence_8
See also Type I collagen_section_2
Type I collagen_unordered_list_0
Credits to the contents of this page go to the authors of the corresponding Wikipedia page: en.wikipedia.org/wiki/Type I collagen.